During the 8,293 at-bats in his career, Lofton has an average at the plate of .299 with 2,477 base hits. He has hit it out of the park 130 times, as well as 3,497 total bases and a .081 slugging percentage. Lofton has recorded a walk 962 times while being called out on strikes on 1,039 chances. He has accrued 1,552 runs and notched 796 RBIs. His OBP is .371 and he has a career OPS of .452.
On the campaign, Lofton has scored 24 runs, amassed 15 RBI and has 0 home runs. He has earned a walk 17 times and has accumulated an OBP of .344. Lofton has compiled 49 base hits in 173 at-bats for an average at the plate of .283. He has struck out 23 times while earning 64 bases in total. He has an OPS of 0.714 as well as a SLG of .370.
| Year | Team | BA | HR | H | BB | R | RBI | OBP | PA | AB | OPS | OPS+ | 2B | 3B | G | SLG | SB | CS | TB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Career | .299 | 130 | 2,428 | 945 | 1,528 | 781 | .372 | 9,235 | 8,120 | .794 | 107 | 383 | 116 | 2,103 | .423 | 622 | 160 | 3,433 | 1,016 | |
| 2007 | TOT | .296 | 7 | 145 | 56 | 86 | 38 | .367 | 559 | 490 | .781 | 105 | 25 | 6 | 136 | .414 | 23 | 7 | 203 | 51 |
| 2007 | TEX | .303 | 7 | 96 | 39 | 62 | 23 | .380 | 363 | 317 | .818 | 115 | 16 | 3 | 84 | .438 | 21 | 4 | 139 | 28 |
| 2007 | CLE | .283 | 0 | 49 | 17 | 24 | 15 | .344 | 196 | 173 | .714 | 88 | 9 | 3 | 52 | .370 | 2 | 3 | 64 | 23 |
| 2006 | LAD | .301 | 3 | 141 | 45 | 79 | 41 | .360 | 522 | 469 | .763 | 95 | 15 | 12 | 129 | .403 | 32 | 5 | 189 | 42 |
| 2005 | PHI | .335 | 2 | 123 | 32 | 67 | 36 | .392 | 406 | 367 | .811 | 109 | 15 | 5 | 110 | .420 | 22 | 3 | 154 | 41 |
| 2004 | NYY | .275 | 3 | 76 | 31 | 51 | 18 | .346 | 313 | 276 | .741 | 95 | 10 | 7 | 83 | .395 | 7 | 3 | 109 | 27 |
| 2003 | TOT | .296 | 12 | 162 | 46 | 97 | 46 | .352 | 610 | 547 | .801 | 106 | 32 | 8 | 140 | .450 | 30 | 9 | 246 | 51 |
| 2003 | PIT | .277 | 9 | 94 | 28 | 58 | 26 | .333 | 374 | 339 | .770 | 98 | 19 | 4 | 84 | .437 | 18 | 5 | 148 | 29 |
| 2003 | CHC | .327 | 3 | 68 | 18 | 39 | 20 | .381 | 236 | 208 | .852 | 120 | 13 | 4 | 56 | .471 | 12 | 4 | 98 | 22 |
| 2002 | TOT | .261 | 11 | 139 | 72 | 98 | 51 | .350 | 611 | 532 | .763 | 103 | 30 | 9 | 139 | .414 | 29 | 11 | 220 | 73 |
| 2002 | CHW | .259 | 8 | 91 | 49 | 68 | 42 | .348 | 406 | 352 | .766 | 102 | 20 | 6 | 93 | .418 | 22 | 8 | 147 | 51 |
| 2002 | SFG | .267 | 3 | 48 | 23 | 30 | 9 | .353 | 205 | 180 | .758 | 104 | 10 | 3 | 46 | .406 | 7 | 3 | 73 | 22 |
| 2001 | CLE | .261 | 14 | 135 | 47 | 91 | 66 | .322 | 576 | 517 | .721 | 89 | 21 | 4 | 133 | .398 | 16 | 8 | 206 | 69 |
| 2000 | CLE | .278 | 15 | 151 | 79 | 107 | 73 | .369 | 640 | 543 | .791 | 100 | 23 | 5 | 137 | .422 | 30 | 7 | 229 | 72 |
| 1999 | CLE | .301 | 7 | 140 | 79 | 110 | 39 | .405 | 561 | 465 | .838 | 112 | 28 | 6 | 120 | .432 | 25 | 6 | 201 | 84 |
| 1998 | CLE | .282 | 12 | 169 | 87 | 101 | 64 | .371 | 698 | 600 | .785 | 102 | 31 | 6 | 154 | .413 | 54 | 10 | 248 | 80 |
| 1997 | ATL | .333 | 5 | 164 | 64 | 90 | 48 | .409 | 564 | 493 | .837 | 119 | 20 | 6 | 122 | .428 | 27 | 20 | 211 | 83 |
| 1996 | CLE | .317 | 14 | 210 | 61 | 132 | 67 | .372 | 736 | 662 | .817 | 107 | 35 | 4 | 154 | .446 | 75 | 17 | 295 | 82 |
| 1995 | CLE | .310 | 7 | 149 | 40 | 93 | 53 | .362 | 529 | 481 | .815 | 110 | 22 | 13 | 118 | .453 | 54 | 15 | 218 | 49 |
| 1994 | CLE | .349 | 12 | 160 | 52 | 105 | 57 | .412 | 523 | 459 | .948 | 145 | 32 | 9 | 112 | .536 | 60 | 12 | 246 | 56 |
| 1993 | CLE | .325 | 1 | 185 | 81 | 116 | 42 | .408 | 657 | 569 | .815 | 121 | 28 | 8 | 148 | .408 | 70 | 14 | 232 | 83 |
| 1992 | CLE | .285 | 5 | 164 | 68 | 96 | 42 | .362 | 651 | 576 | .726 | 107 | 15 | 8 | 148 | .365 | 66 | 12 | 210 | 54 |
| 1991 | HOU | .203 | 0 | 15 | 5 | 9 | 0 | .253 | 79 | 74 | .469 | 38 | 1 | 0 | 20 | .216 | 2 | 1 | 16 | 19 |